The Substance

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R HD 2h 21m

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

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Cast
Crew

Demi Moore

As Elisabeth
Margaret Qualley

As Sue
Dennis Quaid

As Harvey
Edward Hamilton-Clark

As Fred
Gore Abrams

As Oliver
Oscar Lesage

As Troy
Christian Erickson

As Man at Diner
Robin Greer

As Male Nurse
Tom Morton

As Doctor
Hugo Diego Garcia

As Diego - Boyfriend
Daniel Knight

As Casting Director
Jonathon Carley

As Assistant Casting Director
Jiselle Henderkott

As Girl Auditioning / New Year's Eve Show Dancer
Akil Wingate

As TV Host
Vincent Colombe

As Man in Suit #1 - Harvey's Office
Billy Bentley

As Man in Suit #2
Lennard Ridsdale

As Man in Suit #3
Jordan Ford Silver

As Assistant Director - Pump It Up Show
Oscar Salem

As 2nd Assistant Director - Pump It Up Show
Viviane Bossina

As Sue's Assistant
Matthew Luret

As Floor Runner
Jana Bittnerová

As Maria
Olivier Raynal

As Alan - 2nd Agent
Tiffany Hofstetter

As Stylist
Nicolas Royer

As Guy in the Elevator
Nathan Rippy

As Assistant Director - New Year's Eve Show
Manon Arizmendi

As Little Girl - New Year's Eve Show
Virginie Kotlinski

As Mother - New Year's Eve Show
Brett Gillen

As Director of Photography - New Year's Eve Show
Charlotte Marquardt

As Screaming Woman
Léa Hengl

As Screaming Woman
Gaëlle Raymond

As Screaming Woman
Claire Lemaire

As Screaming Woman
Lila Boughoufala

As Screaming Woman
Aurélien Lorgnier

As Screaming Man
Ivan Sellier

As Screaming Man
Philip Schurer

As Screaming Man
Christian Bourmier

As Shareholder
Martin Graham

As Shareholder
Christian Bordeleau

As Shareholder
Patrick Hamel

As Shareholder
Didier Dhondt

As Shareholder
Jacques-Yves Dorges

As Shareholder
Jean-Claude Matthey

As Shareholder
Olivier Jarcin

As Shareholder
Jean-Luc Magneron

As Shareholder
Charlotte Murray

As Allison - Diner Waitress
Aaron Kahn

As Greeting Person
Gabriela Arnon

As Greeting Person
Nancy Josephson Lahoussine

As Greeting Person
Andrew Eldridge

As Greeting Person
Denise Powers

As Greeting Person
Bryan Jones

As Greeting Person
Adam Carage

As Happy Birthday Person
Maria McClurg

As Happy Birthday Person
Andrew Desmond

As Happy Birthday Person
Rebecca Lafont

As Happy Birthday Person
Laura Puech

As Isabella
Ryan Chidester

As Stagehand
Cécile Vogt

As Elisabeth (Young) - Walk of Fame / Pump It Up Show Dancer
Yannick Guérin

As Clumsy Burger Guy - Walk of Fame
Jean Miel

As Worker Walk of Fame
Paul Descoings

As Worker Walk of Fame
Benoit Lévêque

As Worker Walk of Fame
Arthur Molinet

As Cocktail Bartender
Manon Sachot

As Cocktail Lounge Couple
Bastien Jorelle

As Cocktail Lounge Couple
Kelly Hoarau

As Female Assistant - Towel
Michel Juskiewicz

As George - Harvey's Friend
Louise Greggory

As Restaurant Waitress
Christophe Sartirano

As Guy Looking at Sue
Florent Torres

As Guy Looking at Sue
Romain Caldeira

As Billboard Technician
Barthelemy Thomas

As Billboard Technician
Axel Baille

As Photographer
Ashley Lambert

As Additional Voices (voice)
Ranjani Brow

As Additional Voices (voice)
Chase Fein

As Additional Voices (voice)
Shane Sweet

As Additional Voices (voice)
William Calvert

As Additional Voices (voice)
Michael Corbett

As Additional Voices (voice)
Stephen Apostolina

As Additional Voices (voice)
Yann Bean

As The Substance (voice)
Audjyan Alcide

As Pump It Up Show Dancer
Jonathan Jenvrin

As Pump It Up Show Dancer
Mimi Maury

As Pump It Up Show Dancer
Amelye Solange

As Pump It Up Show Dancer
Kévin Table

As Pump It Up Show Dancer
Laura Boera

As Sparkle Your Life Show Dancer
Cissy Duc

As Sparkle Your Life Show Dancer
Sophie Mercier

As Sparkle Your Life Show Dancer
Marie Valton

As Sparkle Your Life Show Dancer
Katrina Budzynski

As New Year's Eve Show Dancer
Alicia Maury

As New Year's Eve Show Dancer
Megane Adamik

As New Year's Eve Show Dancer
Annalisa Pagnotta

As New Year's Eve Show Dancer
Maelle Dantigny

As New Year's Eve Show Dancer
Aleksandra Kedzierska Fontaine

As New Year's Eve Show Dancer
Pauline Sagetat

As New Year's Eve Show Dancer
Agustina Fitzsimons

As New Year's Eve Show Dancer
Elena Shcheglova

As New Year's Eve Show Dancer
Eve Marchant

As New Year's Eve Show Dancer
Lola Donati

As New Year's Eve Show Dancer
Kate Matthews

As New Year's Eve Show Dancer
Ophélie Jonard

As New Year's Eve Show Dancer
Pauline Richard

As New Year's Eve Show Dancer
Laureen Cappelliez

As New Year's Eve Show Dancer
Daria Panchenko

As New Year's Eve Show Dancer
Delphine Beaulieu

As New Year's Eve Show Dancer
Victoria Brun

As New Year's Eve Show Dancer
Cara Chapman

As New Year's Eve Show Dancer
Katharine Matthews

As New Year's Eve Show Dancer
Alexandra Faget

As New Year's Eve Show Dancer
Clémence Juville

As New Year's Eve Show Dancer
Margot L'Entete

As New Year's Eve Show Dancer
Hillary Sukhonos

As New Year's Eve Show Dancer
Matthew Géczy

As Bob Haswell (uncredited)
Namory Bakayoko

As Silhouette (uncredited)
Gregory Defleur

As Happy Birthday Person (uncredited)
Coralie Fargeat

As (uncredited)

Anne Juin

Third Assistant Director
Erik Baiers

Executive Producer
Matthieu de la Mortière

First Assistant Director
Stanislas Reydellet

Production Design
Frédérique Arguello

Hair Department Head
Marie Bouvet

Stunt Double
Jérôme Gaspard

Stunt Coordinator
Richard Martin

Prosthetics Sculptor
Cécilia Blom

Set Decoration
Denise Boccacci

Prosthetic Makeup Artist
Bryan Jones

Visual Effects Supervisor
Frédéric Balmer

Special Effects Makeup Artist
Andrea Leanza

Prosthetics Sculptor
Benjamin Kračun

Director of Photography
Jérôme Eltabet

Editor
Sebastian Lochmann

Concept Artist
Krystell Morantin

Assistant Art Director
Arthur Delapierre

Stunts
Laure Caniaux

First Assistant Camera
Guillemette Buffet

Stunt Double
Vianne Burquier

Camera Intern
Steve de Rocco

Camera Operator
Thomas Gros

Key Grip
William Renaud

Grip
Nadege Marti

Location Scout
Stephane Girondeaud

Stunts
Chloè Acher

Second Assistant Camera
Marie Sergeant

Stunts
Olivier Maurin

Electrician
Edouard Alvernhe

Electrician
Charles Droudun

Electrician
Stella Libert

First Assistant Camera
Ludovic Tobaldi

Steadicam Operator
Noémie Lance

Location Manager
Fabien Pascal

Colorist
Catherine Georges

Camera Operator
Jonas Poignant

Third Assistant Camera
Eddy Trouillot

Grip
Camille Damag

Costume Supervisor
Joffrey Darel

Stunt Driver
Lucile Perez

Stunts
Marie-Sophie Daniel

First Assistant Camera
Fabienne Menguy

Costume Supervisor
Ahmed Chouikhi

Stunts
Guillaume Lemerle

Gaffer
Nahi Margot

Electrician
Katia Sourzac

Location Production Assistant
Benjamin Bouygues-Faugeron

Property Buyer
Jérémie Delaboudinière

Stunts
Tanguy Goasguen

Additional Grip
Gustin Guillaume

First Assistant Camera
Olivier Sargatal

Best Boy Electric
Céline Richard

Stunts
Benjamin Colleye

Additional First Assistant Camera
Yann Festinger

Video Assist Operator
Benjamin Durfort

Assistant Editor
Baptiste Bonin

Props
Baptiste Herment

Production Accountant
Baptiste Marnière

Digital Imaging Technician
Christine Tamalet

Still Photographer
Coralie Fargeat

Director
Eric Fellner

Producer
Coralie Fargeat

Producer
Tim Bevan

Producer
Alexandra Loewy

Executive Producer
Nicolas Royer

Executive Producer
Raffertie

Original Music Composer
Oriane Cattiaux

Makeup Artist
Marison De

Special Effects Makeup Artist
Sandrine Denis

Special Effects Makeup Artist
Louis Tellier

Third Assistant Director
Honorine Sutter

Assistant Production Manager
Jean Miel

Special Effects Supervisor
Benjamin Celliez

Unit Production Manager
Elise Duvignau

Props
Abraham Goldblat

Post Production Supervisor
Brian Kinney

Special Effects Makeup Artist
Julia Besnier

Production Accountant
Clément Audebrand

Third Assistant Director
Stéphanie Guillon

Key Makeup Artist
Caroline Vlieghe

Hairstylist
Pierre-Yves Frohard

Production Coordinator
Mateo Cejoco

Third Assistant Director
Barthelemy Thomas

Set Dresser
Amélie Meseguer

Assistant Set Decoration
Mélissa Jacob

Additional Hairstylist
Louis Lion

Digital Compositor
Olivier Afonso

Special Effects Makeup Artist
Lucky Nguyen

Makeup Artist
Cynthia Scigliuto

Makeup Artist
Benoit Seiller

Second Assistant Director
Coralie Fargeat

Editor
Téo L'Huillier

Digital Compositor
Dave Elsey

Prosthetic Supervisor
Louis Celnik

Carpenter
Lou Elsey

Prosthetic Supervisor
Bryony Rumble

Special Effects Makeup Artist
Tiva Nagchin

Post Production Supervisor
Marion Didier

Assistant Art Director
Guillaume Le Gouez

Visual Effects Supervisor
Christophe Arnaud

Additional Second Assistant Camera
Isalys Gillet

Location Assistant
Elsa Rolland

Assistant Property Master
Elsa Manunta

Set Costumer
Marianne Huet

Script Supervisor
Olaf Taittinger

Special Effects
Louis Auger

Digital Compositor
Chloé Zobel

Property Master
Jacob Rogers

Digital Compositor
Jacques-Emmanuel Astor

Extras Casting
Jimmy Zhao

First Assistant Editor
Guillaume Baurez

Music Supervisor
Marjane Texier

Graphic Designer
Thomas Burgess

Steadicam Operator
Christophe Riso

Assistant Location Manager
Guillaume Billy

Camera Trainee
Raphaëlle Beck

Extras Casting
Steve Sebir

Assistant Location Manager
Aurélie Boutet

Casting Assistant
Pierre-Olivier Persin

Prosthetics
Pierre-Olivier Persin

Makeup Effects Designer
Marion De Villechabrolle

Set Decoration
Valentin Féron

Editor
Stéphane Bécimol

Art Direction
Emmanuelle Youchnovski

Costume Designer
Victor Praud

Sound Re-Recording Mixer
Valérie Deloof

Sound Designer
Judah Getz

ADR Mixer
Patrick Christensen

ADR Mixer
Emmanuelle Villard

Sound Mixer
Olga Pasternak

Supervising Dialogue Editor
Thomas Pichon

Dialogue Editor
Stéphane Thiébaut

Sound Re-Recording Mixer
Anna Devillaire

ADR Editor
Margaux Peyre

Boom Operator
Antoine Swertvaegher

Foley Editor
Grégory Vincent

Foley Artist
Claire Bernengo

Boom Operator
Valérie Deloof

Sound Editor
Victor Fleurant

Sound Editor
Lucien Richardson

Supervising Dialogue Editor
Laure Cochener

Casting
Coralie Fargeat

Writer
Amélie Meseguer

Art Direction
Arnaud Denis

Art Direction
Gladys Garot

Art Direction
Julie Plumelle

Art Direction
Nathalie Vaïsse

Art Direction
Pierre Procoudine-Gorsky

Visual Effects Producer
Chevin Shafaghi

Visual Effects Supervisor
Serafin Bernfeld

Special Effects Technician
Arthur Weiser

Special Effects Technician
Alexandrine Mauvezin-Bosque

Set Dresser
Marilyne Scarselli

Key Hair Stylist
Jean-Marc Benois

Additional Hairstylist
Frédérique Arguello

Key Hair Stylist

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